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Harvard University in Cambridge is the oldest institution of higher learning in the United States, Kendall Square in Cambridge has been called "the most innovative square mile on the planet", in reference to the high concentration of entrepreneurial start-ups and quality of innovation which have emerged in the vicinity of the square since 2010.The Massachusetts Bay Colony was named after the indigenous population, the Massachusett, likely derived from a Wôpanâak word muswach8sut, segmented as mus(ây) "big" wach8 "mountain" -s "diminutive" -ut "locative" (the '8' in these words refers to the 'oo' sound according to the Wôpanâak orthographic chart).The Pilgrims were soon followed by other Puritans, who established the Massachusetts Bay Colony at present-day Boston in 1630.Both religious dissent and expansionism resulted in several new colonies being founded shortly after Plymouth and Massachusetts Bay elsewhere in New England.
In 1691, the colonies of Massachusetts Bay and Plymouth were united (along with present-day Maine, which had previously been divided between Massachusetts and New York) into the Province of Massachusetts Bay.
Department of Public Health by the Massachusetts Supreme Judicial Court.
Many prominent American political dynasties have hailed from the state, including the Adams and Kennedy families.
Alternatively, Massachusett has been represented as Moswetuset—from the name of the Moswetuset Hummock (meaning "hill shaped like an arrowhead") in Quincy, where Plymouth Colony commander Myles Standish, hired English military officer, and Squanto, part of the now disappeared Patuxet band of the Wampanoag peoples, met Chief Chickatawbut in 1621.
In the early 1600s, after contact had been made with Europeans, large numbers of the indigenous peoples in the northeast of what is now the United States were killed by virgin soil epidemics such as smallpox, measles, influenza, and perhaps leptospirosis.), officially the Commonwealth of Massachusetts, is the most populous state in the New England region of the northeastern United States.